Organic letters

Highly Enantiospecific Platinum-Catalyzed Cycloisomerizations: Synthesis of Enantioenriched Oxabicycloheptene Derivatives

ET Newcomb, EM Ferreira

文献索引：Newcomb, Eric T.; Ferreira, Eric M. Organic Letters, 2013 , vol. 15, # 7 p. 1772 - 1775

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被引用次数: 12

摘要

Enantiospecific cycloisomerizations of 1, 6-enynes to form oxabicyclo [4.1. 0] heptene derivatives are described. Enantiospecificity is consistently high regardless of alkene or alkyne substitution, providing a general approach to greatly enantioenriched cyclopropanes. Additionally, a model for stereochemical transfer is proposed.