前往化源商城

Synlett

A convenient synthesis of 2-cyano-3-substituted indoles

S Denison, ST Hilton

文献索引:Denison, Sophie; Hilton, Stephen T. Synlett, 2004 , # 15 p. 2806 - 2808

全文:HTML全文

被引用次数: 5

摘要

A new and mild method for the synthesis of 2-cyano-3-substituted indoles is described which is effective on N-unsubstituted indoles. ... Substituted cyanoindoles are important intermediates in the synthesis of heteroaromatic molecules and have found some use in the synthesis of biologically active compounds. [2] [3] Incorporation of the nitrile functionality into substituted indoles has been accomplished via a variety of methods which often involve multi-step routes and harsh, ...