Synthesis of 2-Alkylaminoethanols from Ethanolamine

AC Cope, EM Hancock

文献索引：Cope; Hancock Journal of the American Chemical Society, 1942 , vol. 64, p. 1503,1504

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被引用次数: 44

摘要

Certain disadvantages are inherent in the methods which are available for the preparation of 2-alkylaminoethanols1 RNHCHzCH20H. The reaction of primary amines with ethylene oxide'and with ethylene chlorohydrin2 produces a mixture of mono and dialkylaminoethanols. The reaction of ethanolamine with alkyl halidesa may lead to either secondary or tertiary amino compou'nds. The method described by Goldberg and WF ...