Bis (1 H-2-indolyl) methanones as a novel class of inhibitors of the platelet-derived growth factor receptor kinase

…, S Teller, H Pongratz, H Hufsky…

文献索引：Jackson, Anthony H.; Prasitpan, Noojaree; Shannon, Patrick V. R.; Tinker, Alan C. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 2543 - 2552

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被引用次数: 71

摘要

... Journal ... 34 figure Scheme 1 a. a (A) THF, −78 °C; (B) PDC/PTFA, CH 2 Cl 2 , rt, 2 h to 21 d; (C) either 1. NaOH/H 2 O/EtOH, reflux, 2 to 12 h, or TBAF/THF, 50 °C, 0.5 to 4 h; (D) THF, −78 °C, CO 2 , CH 2 Cl 2 , 6 M HCl, reflux, 1 h; (E) SOCl 2 , reflux, 2 h; F: THF, −78 °C to rt, 12 h. ...