Tetrahedron

In (OTf) 3 catalyzed N-benzylation of amines utilizing benzyl alcohols in water

JM Yang, R Jiang, L Wu, XP Xu, SY Wang, SJ Ji

文献索引：Yang, Jin-Ming; Jiang, Ran; Wu, Lin; Xu, Xiao-Ping; Wang, Shun-Yi; Ji, Shun-Jun Tetrahedron, 2013 , vol. 69, # 37 p. 7988 - 7994

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被引用次数: 2

摘要

Abstract An In (OTf) 3-catalyzed N-benzylation of amines utilizing benzyl alcohols through direct C–O bond activation has been reported. The reaction was performed in water without any base, additive, ligand or inert gas protection to afford the chem-selective mono-or bis- alkylated aromatic amines in good to excellent yields.