Synthesis of New Bis??imidazole Derivatives

…, P Mucha, A Linden, H Heimgartner

文献索引：Jasinski, Marcin; Mloston, Grzegorz; Mucha, Paulina; Linden, Anthony; Heimgartner, Heinz Helvetica Chimica Acta, 2007 , vol. 90, # 9 p. 1765 - 1780

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被引用次数: 34

摘要

Abstract The reaction of aldimines with α-(hydroxyimino) ketones of type 10 (1, 2-diketone monooximes) was used to prepare 2-unsubstituted imidazole 3-oxides 11 bearing an alkanol chain at N (1)(Scheme 2, Table 1). These products were transformed into the corresponding 2H-imidazol-2-ones 13 and 2H-imidazole-2-thiones 14 by treatment with Ac 2 O and 2, 2, 4, 4-tetramethylcyclobutane-1, 3-dithione, respectively (Scheme 3). The ...