Tetrahedron

Reaction of 1-alkyl/aryl-3-amino-1H, 3H-quinoline-2, 4-diones with urea. Synthetic route to novel 3-(3-acylureido)-2, 3-dihydro-1H-indol-2-ones, 4-alkylidene-1′ H- …

A Klásek, K Kořistek, A Lyčka, M Holčapek

文献索引：Klasek, Antonin; Koristek, Kamil; Lycka, Antonin; Holcapek, Michal Tetrahedron, 2003 , vol. 59, # 28 p. 5279 - 5288

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被引用次数: 26

摘要

1-Substituted 3-alkyl/aryl-3-amino-1H, 3H-quinoline-2, 4-diones react with urea in boiling acetic acid to give products depending on the type of substitution in position 3 and at the nitrogen atom of the 3-amino group. Starting compounds bearing a primary amino group in position 3 give 3-(3-acylureido)-2, 3-dihydro-1H-indol-2-ones. Starting compounds bearing a secondary amino group in position 3 react according to the character of the other ...