Synthetic Communications

A New Synthesis and the 13C-NMR OF β-Cyperone 1, 3-Dibromo-2-Pentene, A New Ethyl Vinyl Ketone Equivalent

RB Gammill, TA Bryson

文献索引：Gammill,R.B.; Bryson,T.A. Synthetic Communications, 1976 , vol. 6, p. 209 - 215

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被引用次数: 7

摘要

Abstract In connection with another study underway in this lab we have been investigating the use of vinylogous thioester 1 as a synthon for sesquiterpene synthesis. We have found that 1 is useful for ring annelations and introduction of multiple substituents when pursuing carbocyclic synthesis. In recent studies with thioesters we have found that the lithium enolate of 1 (LDA/THF) will undergo 1, 4-addition to Michael acceptors such as ethyl vinyl ketone ( ...