Platinum (II) complexes of reduced amino acid ester Schiff bases: Synthesis, characterization, and antitumor activity

…, C Wang, Y Qiao, XY Yang, XX Hua, JL Du

文献索引：Li, Li-Jun; Wang, Cheng; Qiao, Yu; Yang, Xiao-Yan; Hua, Xing-Xing; Du, Jian-Long Research on Chemical Intermediates, 2014 , vol. 40, # 1 p. 413 - 424

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被引用次数: 2

摘要

Abstract A series of platinum (II) complexes of reduced amino acid esters Schiff bases were synthesized as potential anticancer agents and characterized by 1 H NMR, EA, IR, and molar conductivity. These compounds were tested for their DNA interaction with salmon sperm DNA by ultraviolet spectrum and CD spectrum, and their in vitro anticancer activities have been validated against HL-60, KB, BGC-823, and Bel-7402 cell lines by MTT assay. ...