Synlett

Direct Cobalt-Catalyzed Conjugate Addition of Functionalized Aryl Halides and Triflates: A New Strategy for the Conjugate Addition onto Methyl Vinyl Ketone

M Amatore, C Gosmini

文献索引：Amatore, Muriel; Gosmini, Corinne Synlett, 2009 , # 7 p. 1073 - 1076

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被引用次数: 11

摘要

Abstract An efficient cobalt-catalyzed method for the direct conjugate addition of functionalized aryl halides or triflates onto methyl vinyl ketone is described. The experimentally simple procedure relies on the use of a catalytic system consisting of CoBr 2 (Bpy) and zinc and does not require the preformation of a stoichiometric organometallic species. The approach described herein displays considerable functional-group ...