Duocarmycins binding to DNA investigated by molecular simulation

…, U Rothlisberger, P Carloni

文献索引：Parrish, Jay P.; Kastrinsky, David B.; Boger, Dale L. Organic Letters, 2003 , vol. 5, # 14 p. 2577 - 2579

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被引用次数: 25

摘要

... Volume: Page: ... The corresponding reaction in water does not occur at physiological pH, while its t 1/2 is 177 h at pH 3. 6 The structurally related NBOC−DSA compound, in which ring B is replaced by a tert-butyl group (Figure 1), is 3−4 orders ... 19 (ii) Boger et al. ...