Mild Copper??Catalyzed Vinylation Reactions of Azoles and Phenols with Vinyl Bromides

…, A Ouali, B Renard, JF Spindler

文献索引：Taillefer, Marc; Ouali, Armelle; Renard, Brice; Spindler, Jean-Francis Chemistry - A European Journal, 2006 , vol. 12, # 20 p. 5301 - 5313

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被引用次数: 102

摘要

Abstract An efficient and straightforward copper-catalyzed method allowing vinylation of N-or O-nucleophiles with di-or trisubstituted vinyl bromides is reported. The procedure is applicable to a broad range of substrates since N-vinylation of mono-, di-, and triazoles as well as O-vinylation of phenol derivatives can be performed with catalytic amounts of copper iodide and inexpensive nitrogen ligands 3 or 8. In the case of more hindered vinyl ...