Abstract The conditions for the formation of N-substituted decahydroacridine-1, 8-diones from α-R-methylenebiscyclohexane-1, 3-diones and 5, 5-dimethyl-3-(N-methylamino)-2- cyclohexen-1-one in ethanol, isopropanol, and DMSO have been studied. Methods have been developed for preparation of 1, 8-dioxo-10-methyldecahydroacridines which contain furyl and 5-nitrofuryl substituents at the 9 position.
[Chen, Yuhpyng Liang; Mariano, Patrick S.; Little, Garrick M.; O'Brien, Daniel; Huesmann, Peter L. Journal of Organic Chemistry, 1981 , vol. 46, # 23 p. 4643 - 4654]