Synthesis and biological properties of pyrimido [4.5-b][1.4]-thiazine derivatives

AS Sokolova, NA Ryabokon', YA Ershova…

文献索引：Sokolova,A.S. et al. Pharmaceutical Chemistry Journal, 1977 , vol. 11, # 9 p. 1205 - 1210 Khimiko-Farmatsevticheskii Zhurnal, 1977 , vol. 11, # 9 p. 49 - 54

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被引用次数: 1

摘要

In recent years considerable research has been conducted in the search for folic acid (FA) antagonists which show selective toxicity toward tumor cells and are capable of exerting a therapeutic effect in cases of resistance to aminopterin and methotrexate. Such research