Journal of fluorine chemistry

Preparation of acyl fluorides with hydrogen fluoride-pyridine and 1, 3-dicyclohexylcarbodiimide

C Chen, CT Chien, CH Su

文献索引：Chen, Chinpiao; Chien, Chin-Tzu; Su, Chu-Hsiang Journal of Fluorine Chemistry, 2002 , vol. 115, # 1 p. 75 - 77

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被引用次数: 16

摘要

This work presents an efficient procedure for preparing acyl fluorides by simply reacting carboxylic acid with hydrogen fluoride-pyridine and 1, 3-dicyclohexylcarbodiimide (DCC) in dichloromethane. The acyl fluorides were converted in situ to the corresponding benzyl carboxylic esters by adding benzyl alcohol and triethylamine to the reaction mixture.