The Journal of organic chemistry

Transition-Metal-Catalyzed Chemoselective Methylenation of Dicarbonyl Substrates

H Lebel, M Davi, GT Stokłosa

文献索引：Lebel, Helene; Davi, Michael; Stoklosa, Grzegorz T. Journal of Organic Chemistry, 2008 , vol. 73, # 17 p. 6828 - 6830

全文：HTML全文

被引用次数: 6

摘要

Rhodium-and copper-catalyzed methylenation reactions with trimethylsilyldiazomethane, triphenylphosphine, and 2-propanol were used to react chemoselectively with aldehydes, alkoxymethylketones, and trifluoromethylketones in substrates also containing a less reactive carbonyl group. Terminal alkenes were obtained in high yields, and no protecting group was necessary in the methylenation process.