Thioureas containing the N, S-heterocyclic ring are multidentate nitrogen–sulfur donors. Such compounds and their metal complexes were found to possess a wide range of biological applications [1–3 View all references]. The occurrence of thiazoles as a structural unit in biologically active products such as vitamin B 1 , bacitracin, penicillin and luciferin, their ability to bind proteins, DNA and RNA, as well as the exceptional range of antitmor, antiviral, antidiabetic, ...