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Synthesis and biological activity of 2-sila-5-morpholinones

EA Mamaeva, OV Agafonova, VN Negrebetskii…

文献索引:Mamaeva, E.A.; Agafonova, O.V.; Negrebetskii, V.N.; Shipov, A.G.; Baukov, Yu.I.; Losev, A.S. Pharmaceutical Chemistry Journal, 1994 , vol. 28, # 6 p. 396 - 400 Khimiko-Farmatsevticheskii Zhurnal, 1994 , vol. 28, # 6 p. 26 - 29

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摘要

Organosilicon compounds possess a broad spectrum of biological activity [2]. However only a few are used in pharmacology [6]. The search for regulators of extreme states among organosilicon compounds is limited and has been carried out only among compounds of hypervalent silicon [4, 5]. In view of the possible role of silicon in effecting adaptation mechanisms during the action of various factors (hypoxia, action of chemical agents, supercooling, combined stress), it ...