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Heterocycles

A synthesis of N-formylenamides of isoquinoline

…, S Nikolova, S Statkova-Abeghe, P Angelov

文献索引:Ivanov, Iliyan; Nikolova, Stoyanka; Statkova-Abeghe, Stela; Angelov, Plamen Heterocycles, 2006 , vol. 68, # 2 p. 387 - 393

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摘要

Abstract–N-Formylenamides of isoquinoline (6) were obtained from N-[2-(2-acyl-4, 5- dimethoxyphenyl) ethyl] formamides (5) by cyclization in the presence of catalytic amount of p-toluensulfonic acid. The starting keto formamides (5) were obtained by acylation of a N-[2- (3, 4-dimethoxyphenyl) ethyl] formamides (1) with carboxylic acids or their anhydrides in polyphosphoric acid (PPA).