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Synthesis and reactivity of 2, 6??diamino??4??methyl??3??pyridinecarbonitrile

AR Katritzky, S Rachwal, TP Smith…

文献索引:Katritzky, Alan R.; Rachwal, Stanislaw; Smith, Terrance P.; Steel, Peter J. Journal of Heterocyclic Chemistry, 1995 , vol. 32, # 3 p. 979 - 984

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被引用次数: 8

摘要

Abstract 2, 6-Dihydroxy-4-methyl-3-pyridinecarbonitrile is converted via its 2, 6-dichloro analog into the corresponding 2-amino-6-chloro, 2-chloro-6-amino, and 2, 6-diamino derivatives. The last reacts with benzene-sulfonyl chloride to yield a tris-sulfonyl derivative, the structure of which is demonstrated by X-ray analysis.