Tetrahedron

The synthesis of 1-aminobenzylphosphonic acids from benzylidenediphenylmethylamines, for use as structural units in antithrombotic tripeptides

…, G Patel, S Elgendy, JA Baban, G Claeson, VV Kakkar…

文献索引：Green, Donovan; Patel, Geeta; Elgendy, Said; Baban, Jehan A.; Claeson, Goran; Kakkar, Vijay V.; Deadman, John Tetrahedron, 1994 , vol. 50, # 17 p. 5099 - 5108

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被引用次数: 34

摘要

Acid hydrolyses of O, O-dimethyl or O, O-diethyl 1-(diphenylmethylamino) benzylphosphonate intermediates 2, formed from the addition at elevated temperature of dimethyl or diethyl phosphite to benzylidenediphenylmethylamines 1, generates 1- aminobenzylphosphonic acids 3 in good yield.