An Improved Synthesis Route to Functionalized 2-Alkyn-1-ylboronates: Useful Intermediates for the Preparation of α-Allenic Alcohols

CD Roy, R Soundararajan, HC Brown

文献索引：Roy, Chandra D.; Soundararajan, Raman; Brown, Herbert C. Monatshefte fur Chemie, 2008 , vol. 139, # 3 p. 241 - 249

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被引用次数: 6

摘要

Summary. Functionalized 2-alkyn-1-ylboronates were successfully prepared in good yields by reacting various acyclic and cyclic (iodomethyl) boronates with various alkynyllithium salts. Amongst various (iodomethyl) boronates studied, 2-(iodomethyl)-1, 3, 2-dioxa-4, 4, 5, 5- tetramethylborolane provided improved chemical yields of 2-alkyn-1-ylboronates with pyran- and triisopropylsilyl-substituted alkynyllithium salts. 2-Alkyn-1-ylboronate bearing an acid ...