The reaction of N, N-dimethyl-or N, N-pentamethylene-formamide chlorides with n-butyl, cyclohexyl, and 2, 4-xylyl isocyanides results in the formation of 1: 2-adducts which are readily converted by water to N, N'-disubstituted α-(dialkylamino) malonamides. In the case of N, N-dimethylamide chlorides of acetic, propionic, and benzoic acids, the products are the corresponding N-substituted α-ketoamides resulting from hydrolysis of 1: 1-adducts and ...
