Tetrahedron letters

Photoaddition of alcohols and ethers to flavins in the presence of EDTA

PF Heelis, RF Hartman, SD Rose

文献索引：Heelis, Paul F.; Hartman, Rosemarie F.; Rose, Seth D. Tetrahedron Letters, 1994 , vol. 35, # 33 p. 6053 - 6056

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被引用次数: 2

摘要

Abstract Alcohols and ethers that do not normally photoadd to flavins do so in the presence of EDTA to produce covalent attachment of an alkyl group at C (4a). Thus, irradiation of an aerated solution containing both EDTA and t-butanol resulted in rapid formation of an air- stable, reduced flavin, FlH-C (4a) CH 2 C (CH 3) 2 OH. Similar results were also obtained with ethanol, 1-propanol, 2-propanol, pinacol, poly (ethylene glycol), and dioxane, but not ...