Enantioselective allylation of aromatic amines after in situ generation of an activated cyclometalated iridium catalyst

C Shu, A Leitner, JF Hartwig

文献索引：Shu, Chutian; Leitner, Andreas; Hartwig, John F. Angewandte Chemie - International Edition, 2004 , vol. 43, # 36 p. 4797 - 4800

全文：HTML全文

被引用次数: 141

摘要

Aromatic amines with a stereocenter a to the nitrogen atom are important structural motifs in a number of biologically active compounds.[1] Many of approaches to such structures have been investigated, but each method has limitations. Thus, a highly enantioselective procedure to prepare optically active aromatic amines would be valuable, and an enantioselective route to N-aryl allylic amines would be particularly useful because of the ...