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Tetrahedron: Asymmetry

First enantioselective synthesis of daphneticin and its regioisomer

X Ren, X Chen, K Peng, X Xie, Y Xia, X Pan

文献索引:Ren, Xinfeng; Chen, Xiaochuan; Peng, Kun; Xie, Xingang; Xia, Yamu; Pan, Xinfu Tetrahedron Asymmetry, 2002 , vol. 13, # 16 p. 1799 - 1804

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被引用次数: 33

摘要

Daphneticin 1 has been isolated as a racemic compound 2 from the roots and stems of Daphne tangutica. As a coumarinolignoid, daphneticin showed 4 cytotoxic activity in vitro in the walker-256-carcinosarcomaascites system. Cordell and Lin 3., , , , , , and reported the synthesis of daphneticin under oxidative reaction conditions (horseradish peroxidase and silver oxide). Later, Tanaka et al. 3g described that daphneticin could also prepared using Ph 2 ...