Synthesis and evaluation of antioxidant and antimicrobial properties of thymol containing pyridone moieties

…, YA Pawar, AE Sonawane, SM Bhosale…

文献索引：Nagle; Pawar; Sonawane; Bhosale; More Medicinal Chemistry Research, 2012 , vol. 21, # 7 p. 1395 - 1402

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被引用次数: 2

摘要

Abstract Various derivatives of 1, 2-dihydro-6-(4-hydroxy-5-isopropyl-2-methylphenyl)-2-oxo- 4-arylpyridine-3-carbonitrile (IVa–m) were synthesized and characterized. Their antioxidant and antimicrobial properties were evaluated by measuring their activity in vitro. Among the newly synthesized derivatives IVg, IVh, IVi, IVj, IVk, IVl, and IVm showed good antioxidant activity. However, all derivatives show better antibacterial and antifungal properties than ...