Novel angular furo and thieno-quinolinones: synthesis and preliminary photobiological studies

…, G Menozzi, C Marzano, F Baccichetti, F Bordin

文献索引：Fossa, Paola; Mosti, Luisa; Menozzi, Giulia; Marzano, Cristina; Baccichetti, Franca; Bordin, Franco Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 3 p. 743 - 751

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被引用次数: 47

摘要

A number of new furo and thienoquinolinones carrying an electron-withdrawing function or unsubstituted at the position 3 were synthesized in order to obtain new potential photochemotherapeutic agents with increased antiproliferative activity and decreased toxic side effects. Our interest in studying the SAR of these derivatives also prompted us to investigate the influence of N-methylation on biological activity, by preparing N-methyl ...