Reactivity of 3-iodoimidazo [1, 2-a] pyridines using a Suzuki-Type cross-coupling reaction

…, V Collot, M Hervet, S Rault, A Gueiffier

文献索引：Enguehard, Cecile; Renou, Jean-Louis; Collot, Valerie; Hervet, Maud; Rault, Sylvain; Gueiffier, Alain Journal of Organic Chemistry, 2000 , vol. 65, # 20 p. 6572 - 6575

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被引用次数: 85

摘要

The influence of base and solvent in Suzuki cross-coupling reaction on various 2-substituted- 3-iodoimidazo [1, 2-a] pyridines was reported. The reactivity was largely influenced by nature of the substituent. Optimized yields and shortened times of reaction were obtained using strong bases in DME.

~85%

~68%

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