Synthesis and in vitro antibacterial screening of some new 2, 4, 6-trisubstituted-1, 3, 5-triazine derivatives

R Bhushan Singh, N Das, S Jana…

文献索引：Singh, Ravi Bhushan; Das, Nirupam; Jana, Srabanti; Das, Aparoop Letters in Drug Design and Discovery, 2012 , vol. 9, # 3 p. 316 - 321

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被引用次数: 4

摘要

With an objective to evaluate the antibacterial activity of triazine derivatives, a series of 2, 4, 6-trisubstituted-1, 3, 5-triazine were synthesized and characterized by FTIR, 1H-NMR, 13C- NMR, mass spectroscopy and elemental analysis. The minimum inhibitory concentration (MIC) of the compounds that displayed favourable zone of inhibition was determined by broth microdilution method. Derivatives with morpholinyl substituent (4a and 4i) ...