Tetrahedron letters

An improved synthesis of the antiviral acyclonucleoside 9-(4-hydroxy-3-hydroxymethylbut-1-yl) guanine

MR Harnden, RL Jarvest

文献索引：Harnden, M.R.; Jarvest, R.L. Tetrahedron Letters, 1985 , vol. 26, # 35 p. 4265 - 4268

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被引用次数: 74

摘要

Tetrahedron Letters,Vol.26,No.35,pp 4265-4268,1985 0040-4039/85 $3.00 + .oo Printed in Great Britain ... AN IMPROVED SYNTHESIS OF THE ANTIVIRAL ACYCLONUCLEOSIDE 9-(4-HYDROXY-3-HYDROXYMETHYLBUT-l-YL)GUANINE ... MR Harnden and RL Jarvest Beecham Pharmaceuticals Research Division, Biosciences Research Centre, Great Burgh, Epsom, Surrey KT18 5XQ, UK ... ABSTRACT: Alkylation of 2-amino-6-chloropurine with 5-(2-bromoethyl) ...