Tetrahedron

Synthesis, stereochemistry confirmation and biological activity evaluation of a constituent from Isodon excisus

X Xing, P Ho, G Bourquin, LA Yeh, GD Cuny

文献索引：Xing, Xuechao; Ho, Pei; Bourquin, Geoffroy; Yeh, Li-An; Cuny, Gregory D. Tetrahedron, 2003 , vol. 59, # 50 p. 9961 - 9969

全文：HTML全文

被引用次数: 22

摘要

A synthesis and stereochemistry confirmation of a constituent recently isolated from the whole plant Isodon excisus is reported. An enantioselective catalytic boron-mediated reduction of an α-bromoketone was utilized in the key synthetic transformation. The methodology described herein was also used for the synthesis of the natural product's enantiomer and several derivatives. In addition, the compounds were evaluated for ...