Tetrahedron letters

Conjugate additions to α, β-unsaturated carbonyl compounds in aqueous media

C Petrier, C Dupuy, JL Luche

文献索引：Petrier, C.; Dupuy, C.; Luche, J. L. Tetrahedron Letters, 1986 , vol. 27, # 27 p. 3149 - 3152

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被引用次数: 112

摘要

Abstract Alkyl halides in the presence of zinc copper couple add smoothly to α-enones and α- enals in aqueous solvents. Sonication enhances the efficiency of the process, which leads to the conjugate adducts in high yields. The reaction follows most probably a radical pathway, and can be used for the addition of functionalized groups.