A total synthesis of racemic eriolanin

MR Roberts, RH Schlessinger

文献索引：Roberts, M. R.; Schlessinger, R. H. Journal of the American Chemical Society, 1981 , vol. 103, # 3 p. 724 - 725

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被引用次数: 48

摘要

The lactones eriolanin (1) and eriolangin (2) are members of the rare 1, l O- secoeudesmanolide class of sesquiterpenes. Isolated by Kupchan and co-workers from the chloroform extract of the plant Eirophgllum lanatum Forbes (Composite), these natural products were found to possess significant in vivo activity against P-388 leukemia in mice as well as in vitro activity against cell cultures derived from human carcinoma of the ...