The synthesis of a series of reagents for photoaffinity labeling of the proteins in chromatin is described and discussed. The reagents contain one or two DNA-intercalating groups, a photoprobe, and a fluorometrically detectable group. The syntheses were aimed at supplying the reagents with basic groups. Furthermore, eventual radiolabeling of reagents should be possible. The two intercalating groups are connected by a linker, and the ...
