Tetrahedron letters

A cheap and efficient method for selective para-iodination of aniline derivatives

C Monnereau, E Blart, F Odobel

文献索引：Monnereau, Cyrille; Blart, Errol; Odobel, Fabrice Tetrahedron Letters, 2005 , vol. 46, # 32 p. 5421 - 5423

全文：HTML全文

被引用次数: 20

摘要

However, selective iodination of aniline derivatives in the para-position is quite a complicated task when mild conditions are required. Amongst the numerous examples found in the literature, most of them imply the use of activators such as toxic heavy metals 5 (lead, mercury and chromium), strong oxidising agents 6, 7 and 8 (IO 3 anions, silver complexes, H 2 O 2 and NaOCl), or strong acidic 9 and 10 or basic conditions (trifluoroacetic acid, H 2 SO 4 and ...