Solvent-free synthesis of 2-amino-3-aryl-5-substituted Thiophenes as anti-inflammatory agents using KF-Al2O3 under microwave irradiation

…, A Sadeghi, Z Mirjafary, FM Moghaddam

文献索引：Saeidian, Hamdollah; Sadeghi, Azam; Mirjafary, Zohreh; Moghaddam, Firouz Matloubi Synthetic Communications, 2008 , vol. 38, # 12 p. 2043 - 2053

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被引用次数: 16

摘要

The effort to develop novel drug-designing strategies has attracted great interest in the pharmaceutical industry and organic synthesis. Microwave-assisted solid-phase organic synthesis (MW-SPOS) has been regarded as one of the new important fields in synthetic organic chemistry. MW-SPOS techniques offer a powerful strategy for the discovery and generation of lead heterocyclic compounds. In addition, a solid-phase approach is interesting because ...