In the present article, the results are reported of a study of antimicrobial activity and toxicity of a series of compounds belonging to the class of hydroxymethyl and aminomethyl derivatives of phenylphosphine and phosphine. These are the representatives of acyclic di-(a- hydroxyalkyl) phenylphosphines; 1, 3, 5-dioxaphosph0rinanes and their derivatives; phosphorusboron-containing heterocycles; aminomethyl derivatives of phosphines; 1, 3, 5 ...