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Solvent-Free Microwave-Assisted Preparation of N-(2-(Pyridin-2-yl)-ethyl) sulfonamides

P Ghattas, JW Carlin, SL Murkli Jr…

文献索引:Ghattas, Paul; Carlin, Joseph W.; Murkli, Steven L.; Jacobs, Danielle L. Synthetic Communications, 2014 , vol. 44, # 4 p. 520 - 529

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被引用次数: 1

摘要

Although nitrogen-containing heterocycles and sulfonamides both play crucial roles in the chemical and pharmaceutical industries, surprisingly little research exists that examines the bifunctional N-(2-(pyridin-2-yl)ethyl)sulfonamide scaffold for any potential applications. Retrosynthetic analysis indicates that this skeleton would be well suited for a conjugate addition reaction. However, the ability of 2-vinylpyridine to behave as an acceptor, and of sulfonamides to behave as ...