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Synlett

Efficient Synthesis of Novel Polyfunctionalised 4, 5′-Bithiazol-4′-ol Derivatives

…, P Filippone, FR Perrulli, E Rossi, S Santeusanio

文献索引:Arcadi, Antonio; Attanasi, Orazio A.; Filippone, Paolino; Perrulli, Francesca R.; Rossi, Elisabetta; Santeusanio, Stefania Synlett, 2004 , # 15 p. 2681 - 2684

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被引用次数: 2

摘要

Abstract 2-Thiazolin-4-one derivatives, obtained by reaction of tert-butyl (3-methoxy-1- methyl-3-oxoprop-1-enyl) diazenecarboxylate with aryl thioamides, were transformed into 5- bromoacetyl-4-hydroxythiazole derivatives by polymer-supported reagents and simple work- up procedures. The compounds thus synthesised were coupled with thioamides bearing valuable functional groups affording novel polyfunctionalised 4, 5′-bithiazol-4′-ol ...