The preparation of 5??phenacylisoxazoles and 5??hydroxyphenyl??isoxazoles and??pyrazoles by the condensation of C (a)??dianions with ethyl benzoylacetate and …
MJ Livingston, MF Chick, EO Shealy…
文献索引：Livingston, Melanie J.; Chick, MarLisa F.; Shealy, Ernest O.; Beam, Charles F. Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 215 - 217
Abstract C (α), O-Dilithiooximes and C (α), N-Dilithiophenylhydrazones were prepared in an excess of lithium diisopropylamide (LDA). The former was condensed with ethyl benzoylacetate and methyl salicylate, and the latter condensed with methyl salicylate. The resulting precyclization intermediates were then treated with aqueous acid, which was followed by cyclodehydration to give phenacylisoxazoles and hydroxyphenyl-isoxazoles ...
