... JavaScript is disabled on your browser. Please enable JavaScript to use all the features on this page. Tetrahedron Letters. Volume 22, Issue 39, 1981, Pages 3883–3886. Cover image Cover image. A novel synthesis of the carbapen-2-em derivatives. ... Received 15 June 1981, Available online 12 March 2001. Abstract. A new synthesis of the carbapen-2-em ring system, the basic nucleus of thienamycin and its relatives, is described. References. 1; RDG Cooper; ...