Preparation and antiinflammatory activity of 2-and 4-pyridones

JB Pierce, ZS Ariyan, GS Ovenden

文献索引：Pierce, James Benjamin; Ariyan, Zaven S.; Ovenden, Gaye Stuart Journal of Medicinal Chemistry, 1982 , vol. 25, # 2 p. 131 - 136

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被引用次数: 36

摘要

Reference 18. shifts (parts per million) for the indicated protons. lyzed self-condensation of both benzoyl and acetoacetamides to give both 4-pyridones (3 and 4) and 2-pyridones 1. Jayalakshmi et al. 9 have recently indicated that the self-condensation of N- methylacetoacetamide gives the compound 5 rather than 2 or 1 as claimed previously. Synthetic Aspects. We have found that the self-condensation of N-arylacetoacetamides ...