Tetrahedron letters

First direct fluorination of tyrosine-containing biologically active peptides

D Hebel, KL Kirk, LA Cohen, VM Labroo

文献索引：Hebel, D.; Kirk, K.L.; Cohen, L.A.; Labroo, V.M. Tetrahedron Letters, 1990 , vol. 31, # 5 p. 619 - 622

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被引用次数: 32

摘要

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Using acetyl hypoflurite a regiospecific electrophilic fluorination of the tyrosine ring of the N-terminal tetrapeptide amide (Tyr-D-Ala-Phe-Gly-NH 2 ) sequence of the opiate peptide dermorphin has been achieved in good yields. ... J. Med. Chem., 30 (1987), p. 1538 and references therein.