Solid-Phase Synthesis of Lidocaine and Procainamide Analogues Using Backbone Amide Linker (BAL) Anchoring 1

SK Shannon, MJ Peacock, SA Kates…

文献索引：El-Moselhy, Tarek F.; El-Kersh, Mohamed A.; Nyberg, Fred; Hede, Ragnar; Eldawy, Mohamed A. Medicinal Chemistry Research, 1998 , vol. 8, # 3 p. 163 - 170

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被引用次数: 30

摘要

... compound (2) and its close analogues (series H), an extra chemical step was ... a The overall chemistry is summarized in Scheme 4 (followed by Scheme 5 for ... to create diverse analogues with potentially improved anesthetic, antiarrhythmic, and other pharmaceutical properties. ...