Synthesis of 2"-amino-2"-deoxyarbekacin and its analogs having potent activity against methicillin-resistant Staphylococcus aureus.

…, T Usui, M Ishii, T Kudo, S Gomi, S SHIBAHARA

文献索引：Kondo; Ikeda; Takeuchi; Usui; Ishii; Kudo; Gomi; Shibahara Journal of Antibiotics, 1994 , vol. 47, # 7 p. 821 - 832

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被引用次数: 6

摘要

Based on our studies on the enzymatic modifications of arbekacin by methicillin-resistant Staphylococcus aureus (MRSA), replacement of the 2"-hydroxyl group by an amino group in arbekacin was designed to synthesize derivatives that would be active against MRSA. 2"- ...