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Synthesis of 6-methyl-8H-dibenzo [a, g] quinolizin-8-imines via Reissert compounds

E Reimann, R Hertel, J Krauss

文献索引:Reimann, Eberhard; Hertel, Rainer; Krauss, Juergen Monatshefte fur Chemie, 2008 , vol. 139, # 6 p. 673 - 684

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被引用次数: 4

摘要

Abstract Alkylation of Reissert compounds derived from 3-methylisoquinolines with several 2- cyanobenzylbromides followed by hydrolytic cleavage provided the corresponding 1-benzyl- 3-methylisoquinolines. Treatment of the latter with methylmagnesiumiodide caused cyclization to the title compounds rather than formation of 2-acetylbenzylisoquinolines.