Molecules

Synthesis, Antimycobacterial, Antifungal and Photosynthesis-Inhibiting Activity of Chlorinated N-phenylpyrazine-2-carboxamides†

…, M Vejsova, V Buchta, J Dohnal, J Jampilek, K Kralova

文献索引：Dolezal, Martin; Zitko, Jan; Osicka, Zdenek; Kunes, Jiri; Vejsova, Marcela; Buchta, Vladimir; Dohnal, Jiri; Jampilek, Josef; Kralova, Katarina Molecules, 2010 , vol. 15, # 12 p. 8567 - 8581

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被引用次数: 26

摘要

Abstract A series of sixteen pyrazinamide analogues with the-CONH-linker connecting the pyrazine and benzene rings was synthesized by the condensation of chlorides of substituted pyrazinecarboxylic acids with ring-substituted (chlorine) anilines. The prepared compounds were characterized and evaluated for their antimycobacterial and antifungal activity, and for their ability to inhibit photosynthetic electron transport (PET). 6-Chloro-N-(4-chlorophenyl) ...