An Investigation of the reaction mechanism of the bis-acylation of aromatics with o-Phthaloyl dichlorides: Regioselective synthesis of anthraquinones

…, G Predieri, M Lanfranchi, MA Pellinghelli

文献索引：Sartori; Bigi; Tao; Porta; Maggi; Predieri; Lanfranchi; Pellinghelli Journal of Organic Chemistry, 1995 , vol. 60, # 20 p. 6588 - 6591

全文：HTML全文

被引用次数: 24

摘要

In our previous studies on the template effect in the ortho-regioselective electrophilic acylation of metal phenolatesl we have reported simple and mild reaction conditions for preparing anthraquinones 5 via a one-pot bisacylation of aromatic substrates with o- phthaloyl dichlorides 1 (Scheme 1h2 On the basis of our synthetic and mechanistic studies we thought that the entire process could be easily accomplished due to the temporary loss ...