A new route to lipid hydroperoxides: orbital symmetry controlled ring opening of vinylcyclopropyl bromides

…, DH Roberts, CB Ziegler Jr

文献索引：Porter, Ned A.; Roberts, David H.; Ziegler, Carl B. Journal of the American Chemical Society, 1980 , vol. 102, # 18 p. 5912 - 5913

全文：HTML全文

被引用次数: 11

摘要

Recent reports that diene hydroperoxides are formed from polyunsaturated fatty acids by enzymes present in platelets and polymorphonuclear leukocytes have stimulated interest in this class of compounds. Arachidonic acid (5, 8, 11, 14-eicosatetraenoic acid, 20: 4), for example, is converted to 12-(hydroperoxy) eicosatet-raenoic acid (1 2-HPETE) by a platelet enzyme,',* and an enzyme present in leukocytes converts this fatty acid into 5-( ...